North America has the most cities on The Economist's latest list with 7, followed closely by Asia (6) and Europe (5). Australia is the sole representative from Oceania, but no South American cities made it into the top 20.
20. Frankfurt, Germany
The Economist looked not only at personal safety, but also the digital, health, and infrastructure security of cities. Frankfurt scored #4 on its list of health-secured cities around the world, unsurprising given Germany's overall broad access to world-class healthcare. That ranking wasn't enough to bump Frankfurt up higher in the overall list, however. But it's still impressive to make the list at all!